Cross Flow Filtration TFF System


  • PendoTECH TFF Process Control System? is an optimal solution that adds automation and data collection to a Cross Flow / Tangential Flow Filtration ? TFF) Process.
  • The system includes a powerful yet easy-to-use Graphical User Interface and recipe-based control of the entire concentration and diafiltration process with multiple options for automated diafiltration end points (filtrate weight, conductivity, pH, air in feed line with non-invasive detector, total flow).
  • Pressure measurement and calculation of trans-membrane pressure (TMP) and delta-P with PendoTECH Pressure Sensors? which can be cleaned and re-used extensively or other pressure sensors/transducers.
  • Industry-standard scales & pumps (peristaltic, rotary lobe, diaphragm, etc.) can be interfaced with the system along with other optional accessories to create an advanced yet flexible system that can be configured as needed.
  • It is ideal for process development and a pilot plant where the project requirements change.

Cross Flow Filtration TFF System

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Cross Flow Filtration TFF System

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Product Features

  • Powerful, yet easy-to-use Graphical User Interface
  • Recipe-based control of entire concentration and diafiltration process with multiple options for automated diafiltration end point (filtrate weight, conductivity, pH, air in feed line with noninvasive detector, total flow)
  • Pressure measurement and calculation of trans-membrane pressure (TMP) and delta-P with PendoTECH Pressure Sensors?, which can be cleaned and reused extensively or other pressure sensors/transducers
  • Flow measurement with different flow meter options including flow totalizing (rotary, mag, ultrasonic, Coriolis, etc.)
  • Process control via integration of industry-standard scales & pumps (peristaltic, rotary lobe, diaphragm, etc.)
  • No process scale limitations
  • Conductivity and pH probe inputs with software calibration routines (conductivity transmitter with temperature display, etc.)
  • Inputs available for other probes/sensors with 4 ? 20 milliamp outputs such as UV and temperature
  • Accessory Valves for Diafiltration 1 / 2 control
  • Pressure alarm set-points that will shut down the system; notification set-point warnings that can generate email or text message alerts
  • Optional 2L vessel with low-point drain and stirrer
  • Options for TMP control with non-product contact PendoTECH Throttle Valve?
  • Ability to control Retentate Flow or DeltaP
  • Available with IQ/OQ templates
  • PendoTECH can deliver a system with desired components

Data Sheets

Product Name Product Number  
PendoTECH-Cross-Flow-Filtration-TFF-System.pdf Download